During the second turning of the wheel of Dharma, Sakyamuni Buddha told sentient beings that all things from the five aggregates, or skandhas, to the buddha’s wisdom are empty; all phenomena in samsara and nirvana are empty and beyond conceptual fabrication.
Please note that the concept of emptiness taught in the scriptures and the concept of emptiness in modern physics—whether in quantum physics or engineering technology—are different.
~Depicted from GATEWAY TO VAJRAYANA PATH - Vajrayana Terminology