What Buddhism does acknowledge is that sentient beings do not have free will over their cyclic existence, and that it is not without causes that we keep roaming about involuntarily in samsara. Yet causes and conditions can be changed and improved because they are compounded phenomena.
Fatalists think that everything is predestined and under no circumstances can it be changed. Buddhists do not acknowledge this viewpoint. Buddhism holds that even immutable karma can be changed with the attainment of realization of emptiness or true repentance. It is also owing to the view that compounded phenomena are not predestined, but can be improved, transformed and controlled, that we need to learn the Twelve Nidanas. It can be said that not knowing the Twelve Nidanas is in fact not to know ourselves.
~Depicted from THE RIGHT VIEW - The Twelve Nidanas1—the sequence of cyclic existence
